8-Hydroxy-5-quinolinesulfonic Acid Monohydrate丨CAS 283158-18-9

8-Hydroxy-5-quinolinesulfonic acid monohydrate丨CAS 283158-18-9 is a metal-chelating, fluorescent, and bioactive heterocyclic compound derived from 8-hydroxyquinoline, with an added sulfonic acid group enhancing its water solubility and reactivity. It is primarily used in metal ion detection, fluorescence-based assays, coordination chemistry, and biological research.

1. Metal Chelation and Coordination Chemistry

● Ligand Design: 8-Hydroxy-5-quinolinesulfonic acid monohydrate丨CAS 283158-18-9 serves as a versatile ligand in coordination compounds for:



The sulfonic acid group increases hydrophilicity, enabling the formation of water-soluble metal complexes, valuable for aqueous-phase catalysis and bioinorganic modeling.

2. Analytical and Fluorescent Probes


oReal-time sensing of biologically relevant ions (e.g., zinc, copper)

3. Biological and Pharmaceutical Research



● Antioxidant Studies: Through metal ion chelation, this compound may reduce metal-catalyzed oxidative stress, offering potential applications in:



It may also serve as a scaffold for the synthesis of novel therapeutics, especially in metal-related pathologies like Alzheimer's or Wilson's disease.

4. Environmental and Water Testing

5. Material Science and Surface Chemistry



● Dye-Sensitized Applications: Investigated for use in light-harvesting materials due to its fluorescent and coordination properties.
 

● Exhibits metal-induced fluorescence changes, enabling sensitive and selective fluorescent sensing.


√ Stability and Shelf-Life

8-Hydroxy-5-quinolinesulfonic acid monohydrate丨CAS 283158-18-9 is a versatile, water-soluble chelating agent ideal for metal sensing, bioinorganic studies, and analytical chemistry. Its unique combination of fluorescent properties, coordination ability, and hydrophilic functionality opens doors in sensor technology, environmental testing, biological research, and pharmaceutical development.